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Human carcinogens exposure : biomonitoring and risk assessment

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Garner, R. Colin ; Farmer, Peter B. ; Steel, G. T. ; Wright, Alan S.

Oxford University Press - New York

1991

446 p.

cancer ; carcinogenic effects ; carcinogens ; determination in air ; exposure ; exposure assessment ; exposure tests ; occupational disease

Occupational diseases

English

Bibliogr.;Charts

0-19-963185-9

13.04.3.2-17216

"Approximately one-third of all deaths in the Western world are due to cancer, and epidemiological studies have established that environmental factors play a major role in the disease. Research on humans has so far concentrated on statistical studies that try to link the incidence of cancers to
types of exposure, but this approach is only useful on a gross scale, and the results are necessarily very long in coming. Sensitive procedures are needed to assess the risks of low-level carcinogen exposure, and to determine the relative dangers of exposure to different substances. Researchers are
applying the powerful tools of molecular biology to study DNA damaged by carcinogens to understand the significance of this damage at the level of the individual and its implications for risk assessment. A meeting on this subject took place in July 1989 where researchers presented and compared the
strengths and weaknesses of various research methods, and this volume is a record of those presentations. It provides a valuable reference source for academic and industrial researchers, as well as government regulators, who are interested in the expanding field of "molecular epidemiology"."

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