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Changes in cellular immunity among workers occupationally exposed to styrene in a plastics lamination plant

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"Styrene is a widely used industrial chemical. Immune and hematological parameters were examined in 29 hand laminators and sprayers exposed to styrene for an average of 14 years and in 19 in-factory unexposed controls. The workers performed hand lamination procedures in a production area with an average area airborne styrene level of 139.5 mg/m3. Mean concentration of styrene in the blood of exposed workers was 945.7 g/L and the mean styrene in exhaled air was 38.8 g/L. ...These results suggest immune alterations of cell-mediated immune response of T-lymphocytes and imbalance in leucocyte subsets in peripheral blood of workers exposed to styrene. ..."

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