"Musculoskeletal comorbidities increasingly are prevalent and present specific research challenges and opportunities. Several definitions for musculoskeletal comorbidities exist depending on the patient population and research approach. Population studies document that musculoskeletal problems, defined as arthritis, are the most prevalent condition in the population as a whole and therefore a frequent comorbidity. As adults with disabilities age and as the population as a whole ages, musculoskeletal comorbidities will become increasingly common. Multiple research studies have begun examining the relationships of musculoskeletal conditions to other health conditions in pediatric, middle-aged, and older adults. Multiple specific research approaches are needed to understand predisposing risk factors, prevention, progression, consequences, and treatment strategies for these conditions."

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