Documents connective tissue disorders 2 results

This study explored the association between biomarkers of type I collagen metabolism and exposure to physical workload.Serum concentrations of the biomarkers were found to differ between the groups. The biomarkers reflected a higher anabolism of type I collagen in the exposed group when compared with that of the reference group. An analysis of the effect of the number of patient-handling activities revealed that a higher exposure was associated with higher effective type I collagen synthesis within the exposed group.These results indicate that serum concentrations of these biomarkers of type I collagen metabolism can reflect differences in exposure between contrasting groups, and also varying levels of exposure between persons within an occupation.This study explored the association between biomarkers of type I collagen metabolism and exposure to physical workload.

Cumulative trauma disorders are usually caused by repeated and/or forceful exertions, often in the hand-arm-shoulder region. They predominantly affect soft tissues, such as tendons and ligaments, and nerves and blood vessels. Other causes include static muscle load, mechanical stress, vibration and cord. Details are given of some specific repetitive strain disorders and a table summarises the associations between various disorders and typical body and job activities. An outline is given of ergonomics measures to avoid the more common cumulative trauma disorders.