Documents Everts, Vincent 1 results

This study explored the association between biomarkers of type I collagen metabolism and exposure to physical workload.Serum concentrations of the biomarkers were found to differ between the groups. The biomarkers reflected a higher anabolism of type I collagen in the exposed group when compared with that of the reference group. An analysis of the effect of the number of patient-handling activities revealed that a higher exposure was associated with higher effective type I collagen synthesis within the exposed group.These results indicate that serum concentrations of these biomarkers of type I collagen metabolism can reflect differences in exposure between contrasting groups, and also varying levels of exposure between persons within an occupation.This study explored the association between biomarkers of type I collagen metabolism and exposure to physical workload.