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Scandinavian Journal of Work, Environment and Health - vol. 44 n° 4 -

Scandinavian Journal of Work, Environment and Health

"As part of a large epidemiologic study of particulate health effect, this study aimed to report respirator use among total particulate matter (TPM) samples collected in a major aluminum manufacturing company from 1966‒2013 and evaluate the impact of respirator-use adjustment on exposure estimation."

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Scandinavian Journal of Work, Environment and Health - vol. 26 n° 6 -

Scandinavian Journal of Work, Environment and Health

"Objectives This study investigated the associations between exposure to fluorides and polycyclic aromatic hydrocarbons (PAH) and mortality from nonmalignant diseases among workers in the Norwegian primary aluminum industry.Methods Mortality among 10 857 men, employed for more than 3 years in 1 of 6 aluminum plants, was investigated from 1962 to 1996, giving 239 246 person-years during follow-up. A job-exposure matrix covering all 6 plants was used to estimate the individual exposure to total fluorides and particulate PAH. The observed cause-specific deaths were compared with expected figures calculated from national rates. Dose-response relations were investigated by internal comparisons using Poisson regression and by stratified analyses for standardized mortality ratio. Potential confounding by smoking was investigated in subanalyses restricted to 3 of the plants for which information on smoking habits was accessible. Results Mortality from circulatory disease was slightly lower than expected [SMR 0.95, 95% confidence interval (95%CI) 0.9-1.0], while there was an increased mortality from asthma, emphysema, and chronic bronchitis combined, SMR 1.2 (95% CI 1.0-1.5). Mortality from these diseases was associated with cumulative exposure to fluorides. The rate ratio in the internal analysis rose steadily to 2.5 (95% CI 1.5-4.3) for the upper exposure category. No association was observed between cumulative fluoride exposure or PAH exposure and circulatory mortality. Conclusions The study showed an association between exposure to potroom emissions measured by fluorides and mortality from asthma, emphysema, and chronic bronchitis combined."
"Objectives This study investigated the associations between exposure to fluorides and polycyclic aromatic hydrocarbons (PAH) and mortality from nonmalignant diseases among workers in the Norwegian primary aluminum industry.Methods Mortality among 10 857 men, employed for more than 3 years in 1 of 6 aluminum plants, was investigated from 1962 to 1996, giving 239 246 person-years during follow-up. A job-exposure matrix covering all 6 plants was ...

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Scandinavian Journal of Work, Environment and Health - vol. 26 n° 6 -

Scandinavian Journal of Work, Environment and Health

"Objectives This study investigated associations between exposure to polycyclic aromatic hydrocarbons (PAH) and the incidence of lung, bladder, kidney, and pancreatic cancer among Norwegian aluminum plant workers.Methods Cancer incidence was investigated from 1953 to 1996 among 11 103 men employed for more than 3 years in the industry, giving 272 554 person-years during follow-up. A job exposure matrix was constructed to estimate exposure to particulate PAH and fluorides. The observed cases of cancer were compared with expected figures calculated from national rates. Dose-response relations were investigated by internal comparisons using Poisson regression and stratified analyses for standardized incidence ratio. Potential confounding by smoking was investigated in subanalyses restricted to 3 of the plants.Results The study showed an overall excess for bladder cancer, standardized incidence ratio 1.3 (95% confidence interval 1.1-1.5), which increased with increasing cumulative exposure to PAH and reached a relative risk of about 2 for the upper exposure category in the analysis with 30 years of lag time. There was no association between cumulative PAH exposure and lung cancer, but there were indications of an elevated risk of kidney cancer among the most heavily PAH-exposed persons in the analyses with a lag time of 30 years. For pancreatic cancer we found a higher incidence among the PAH-exposed persons than among the unexposed ones, but no clear dose-response association was found.Conclusions The study showed an association between bladder cancer and exposure to PAH, but gave no support to an association between PAH exposure and lung cancer in the primary aluminum industry."
"Objectives This study investigated associations between exposure to polycyclic aromatic hydrocarbons (PAH) and the incidence of lung, bladder, kidney, and pancreatic cancer among Norwegian aluminum plant workers.Methods Cancer incidence was investigated from 1953 to 1996 among 11 103 men employed for more than 3 years in the industry, giving 272 554 person-years during follow-up. A job exposure matrix was constructed to estimate exposure to ...

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HesaMag - n° 12 -

HesaMag

"En août 2014, le géant américain de l'aluminium, Alcoa, décide de fermer définitivement son usine de Portovesme, située dans la province de Carbonia-Iglesias, la plus pauvre d'Italie, au sud de la Sardaigne. Avec la perte de quelque mille emplois, la région est aujourd'hui un désert social… et écologique car les eaux bordant le site industriel sont contaminées par les métaux lourds et les résidus chimiques. Marqué par ce désastre, l'écrivain italien Angelo Ferracuti a entamé un périple en Islande, à la rencontre des riverains et des travailleurs d'un des sites qui a pris le relais de l'usine sarde."
"En août 2014, le géant américain de l'aluminium, Alcoa, décide de fermer définitivement son usine de Portovesme, située dans la province de Carbonia-Iglesias, la plus pauvre d'Italie, au sud de la Sardaigne. Avec la perte de quelque mille emplois, la région est aujourd'hui un désert social… et écologique car les eaux bordant le site industriel sont contaminées par les métaux lourds et les résidus chimiques. Marqué par ce désastre, l'écrivain ...

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HesaMag - n° 12 -

HesaMag

"In August 2014, the US aluminium giant, Alcoa, decided to permanently close its Portovesme plant in the poorest province of Italy, Carbonia-Iglesias, in southern Sardinia. With the loss of several thousand jobs, the region is now a social desert … and an ecological one too, given that the waters around the industrial site are contaminated with heavy metals and chemical residues. Struck by this disaster, the Italian writer Angelo Ferracuti undertook a journey to Iceland to meet residents and workers at one of the sites that took over from the Sardinian plant."
"In August 2014, the US aluminium giant, Alcoa, decided to permanently close its Portovesme plant in the poorest province of Italy, Carbonia-Iglesias, in southern Sardinia. With the loss of several thousand jobs, the region is now a social desert … and an ecological one too, given that the waters around the industrial site are contaminated with heavy metals and chemical residues. Struck by this disaster, the Italian writer Angelo Ferracuti ...

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IRSST

"Many workers are exposed to a range of particles present on a nanometric scale. In occupational hygiene, it is common to differentiate manufactured nanoparticles (NP) from ultrafine particles (UFP) coming from natural, human or industrial sources. Given that major deficiencies exist in the usual risk assessment approaches for these particles, the objective of this research was to assess occupational UFP and NP exposures. The secondary objective was comprehensive testing of the assessment capabilities regarding occupational NP and UFP exposures in an industrial and laboratory context. Two main types of assessment were performed during this research. The first concerns the assessment of the fine and ultrafine particle concentrations with a particle counter (P-Trak, model 8525), and the second pertains to the assessment of fine and ultrafine particle size distribution with an electrical low pressure impactor (ELPI). The measurements were taken in two welding schools, an aluminium smelter, the research centre of a thermoplastics processing company, and three university laboratories producing and/or using nanoparticles. The results revealed that aluminium smelter workers, people who perform welding tasks, and workers in the thermoplastic processing industry are exposed to UFPs. However, the assessments performed under this study do not reveal high NP concentrations in research laboratories. Only NP production by milling generated detectable NP concentrations. NP handling in glove boxes of two other laboratories seems to prevent worker exposure adequately. There is currently no consensus concerning UFP and NP exposure evaluation measures. However, our findings suggest that the P-Trak is suitable for occupational assessment of UFP concentrations, whereas several uncertainties remain to assess NP exposure, particularly in their agglomerated form. In view of this research, it appears that a characterization and control study of occupational NP and UFP exposure should include assessment of the mass and particle number concentrations, measurement of granulometric distribution and electron microscopic characterization of nanoscale particles."
"Many workers are exposed to a range of particles present on a nanometric scale. In occupational hygiene, it is common to differentiate manufactured nanoparticles (NP) from ultrafine particles (UFP) coming from natural, human or industrial sources. Given that major deficiencies exist in the usual risk assessment approaches for these particles, the objective of this research was to assess occupational UFP and NP exposures. The secondary objective ...

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Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis - n° 516 -

Mutation Research. Fundamental and Molecular Mechanisms of Mutagenesis

"The genetic effects of occupational exposure to low polycyclic aromatic hydrocarbon (PAH) concentrations were investigated in primary aluminium industry workers. The study subjects were employed in a plant that uses pre-baked anode cells, and has relatively low PAH contamination. Forty-two male workers belonging to different job categories (anode fabrication, baking, rodding, electrolysis, maintenance), together with 16 male local residents with no occupational exposure to PAHs were selected for the analysis of micronuclei and DNA lesions in peripheral lymphocytes. The incidence of micronuclei determined in 1000 cytokinesis-blocked cells in each subject was not significantly different between workers and controls (8.5+/-5.4 per thousand versus 9.7+/-4.9 per thousand, respectively), nor between smokers and non-smokers (8.3+/-5.8 per thousand versus 9.2+/-5.1 per thousand), but was significantly (P<0.05) related to the subjects' age. Also the analysis of DNA damage in unstimulated and mitogen-stimulated lymphocytes by single cell gel electrophoresis (SCGE) did not show significant differences between the studied groups (average tail moment values were 0.53+/-0.53 and 0.49+/-0.45 microm in exposed subjects and controls, respectively). "
"The genetic effects of occupational exposure to low polycyclic aromatic hydrocarbon (PAH) concentrations were investigated in primary aluminium industry workers. The study subjects were employed in a plant that uses pre-baked anode cells, and has relatively low PAH contamination. Forty-two male workers belonging to different job categories (anode fabrication, baking, rodding, electrolysis, maintenance), together with 16 male local residents ...

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