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Evaluation des risques pour la reproduction liés aux éthers de glycol

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Article

Cicolella, André

Santé publique

1997

2

157-183

glycol ethers ; pregnancy ; reproductive hazards ; risk assessment ; spermatogenic disturbances ; toxic effects

France

Risk assessment and risk management

French

Bibliogr.

"Glycol ethers (Ge) are a family of substances with a growing use in industrial and domestic products for the two last decades. Ge (group 1 and 2) are experimentally toxic for reproduction and development, at various levels. That begins to be found in humans. Epidemiological studies confirm toxicokinetic data showing humans are more sensitive than animals, because of a low excretion rate of the toxic metabolites. Occupational and consumer exposures are frequently higher than reference concentrations deducted from animal data. They may be involved in the growing number of genital reproductive system and reproduction anomaly, observed in most developed countries. Genetic toxicity is suspected from experimental data, but further investigations are needed."

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