DNA damage and genomic instability among workers formerly and currently exposed to asbestos
Milic, Mirta ; Neri, Monica ; Ceppi, Marcello ; Bruzzone, Marco ; Munnia, Armelle ; Ugolini, Donatella ; Cristaudo, Alfonso ; Bonotti, Alessandra ; Peluso, Marco E. ; Bonassi, Stefano
Scandinavian Journal of Work, Environment and Health
2018
44
4
1-9
asbestos ; biomarker ; DNA ; chromosome changes ; mutagenicity tests ; occupational risks ; long term exposure
Asbestos
http://dx.doi.org/10.5271/sjweh.3721
English
"Surveillance programs of cohorts with past exposure to asbestos lack validated tools for the early identification of subgroups and/or individuals with the highest risk of cancer. Our results show a significant increase of genomic instability in these workers, paving the way for the possible inclusion of the micronuclei (buccal micronucleus) cytome assay in surveillance programs of subjects with past exposure to carcinogens."
Digital
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