Cisplatin. Health-based calculated occupational cancer risk values
Health Council of the Netherlands
Health Council of the Netherlands - The Hague
2005
34 p.
chemicals ; cancer ; carcinogenic effects ; determination of exposure limits ; job exposure relation ; occupational disease ; threshold limit values ; genotoxic effects
Exposure limits
https://www.gezondheidsraad.nl/
English
Bibliogr.
90-5549-562-X
"On request of the Minister of Social Affairs and Employment, the Dutch Expert Committee on Occupational Standards (DECOS), a committee of the Health Council of the Netherlands, estimates the additional cancer risk associated with occupational exposure to substances that have been classified by the European Union or the DECOS as genotoxic carcinogen. In this report the committee presents such estimates for cisplatin, a genotoxic anticancer drug. For the estimation, the committee used the method described in the report ‘Calculating cancer risk due to occupational exposure to genotoxic carcinogens' (Hea95).
The committee estimated that the additional lifetime cancer risk for cisplatin amounts to:
4x10-3 for 40 years of occupational exposure to 5 µg/m3;
4x10-5 for 40 years of occupational exposure to 0.05 µg/m3."
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