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Low-level toxicity of chemicals: no acceptable levels?

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Article

Lanphear, Bruce P.

PLoS ONE

2017

15

12

1-8

chemicals ; toxic substances ; dose response relationship ; threshold limit values ; health impact assessment

Chemicals

https://doi.org/10.1371/journal. pbio.2003066

English

"Over the past 3 decades, in a series of studies on some of the most extensively studied toxic chemicals and pollutants, scientists have found that the amount of toxic chemical linked with the development of a disease or deathÐwhich is central to determining "safe" or "hazardous" levelsÐis proportionately greater at the lowest dose or levels of exposure. These results, which are contrary to the way the United States Environmental Protection Agency (EPA) and other regulatory agencies assess the risk of chemicals, indicate that we have underestimated the impact of toxic chemicals on death and disease. If widely disseminated chemicals and pollutants - like radon, lead, airborne particles, asbestos, tobacco, and benzene - do not exhibit a threshold and are proportionately more toxic at the lowest levels of exposure, we will need to achieve near-zero exposures to protect public health."

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