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"Cette brochure explique les dispositions de l'arrêté royal du 4 août 1996 concernant la protection des travailleurs contre les risques liés à l'exposition à des agents biologiques au travail. En effet, des maladies infectieuses, des allergies, des intoxications peuvent être une des conséquences de l'exposition à certains agents biologiques. Cette réglementation a donc pour objectif de réduire au maximum les risques liés à l'exposition à certains agents biologiques en définissant un ensemble de mesures cohérentes et efficaces pour protéger les travailleurs.
Cette brochure explique les effets des agents biologiques sur la santé, les documents dont doit disposer le travailleur ainsi que la prévention et la gestion des risques"

"The WHO Laboratory Biosafety Manual (LBM) has been in broad use at all levels of clinical and public health laboratories, and other biomedical sectors globally, serving as a de facto global standard that presents best practices and sets trends in biosafety.
LBM encouraged countries to accept and implement basic concepts in biological safety and to develop national codes of practice for the safe handling of biological agents in laboratories within their geographical borders.
This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the risks allows safety measures to be balanced with the actual risk of working with biological agents on a case-by-case basis.
This novel evidence- and risk-based approach will allow optimised resource use and sustainable laboratory biosafety and biosecurity policies and practices that are relevant to their individual circumstances and priorities, enabling equitable access to clinical and public health laboratory tests and biomedical research opportunities without compromising safety."

Fertilization of land with processed sewage sludges, which often contain low levels of pathogens, endotoxins, and trace amounts of industrial and household chemicals, has become common practice in Western Europe, the United States, and Canada. Local governments, however, are increasingly restricting or banning the practice in response to residents reporting adverse health effects. These self-reported illnesses have not been studied and methods for assessing exposures of residential communities to contaminants from processed sewage sludges need to be developed. Methods: To describe and document adverse effects reported by residents, 48 individuals at ten sites in the United States and Canada were questioned about their environmental exposures and symptoms. Information was obtained on five additional cases where an outbreak of staphylococcal infections occurred near a land application site in Robesonia, Pennsylvania. Medical records were reviewed in cases involving hospitalization or other medical treatment. Since most complaints were associated with airborne contaminants, an air dispersion model was used as a means for potentially ruling out exposure to sludge as the cause of adverse effects. Results: Affected residents lived within approximately 1 km of land-application sites and generally complained of irritation (e.g., skin rashes and burning of the eyes, throat, and lungs) after exposure to winds blowing from treated fields. ..."

A large number of workers are currently employed in tasks involving the use of computer based equipment. Much research has been carried out both on prevalence and incidence of ocular and visual disorders as well as on occupational asthenopia. Less attention has been given to investigating the possibility of a microbiological pollution of Video Display Unit (VDU) workstations and to the consequent possible development of work-related ocular infections. The authors investigated the presence of bacteria and fungi on Computer Assisted Design (CAD) workstations and in the conjunctival sac of the operators.

Occupational exposure to bacterial or fungal antigens has been associated with hypersensivity pneumonitis (HP), an immunologically-mediated pulmonary disease. Between August 1995 and April 1996, 34 employees working in machining and assembly areas of an engine manufacturing plant were clinically diagnosed with HP. Of these, 20 employees met an epidemiologic case definition. In a case-control study, no exposure variables, including duration and intensity of metal working fluid (MWF) exposure, were statistically associated with an increased risk of disease. Neither cases nor controls demonstrated precipitin reactivity against unused samples of the seven MWF and two biocides used in the plant. HP cases had a significantly higher prevalence of positive precipitin reactions to used oil soluble and synthetic MWFs. Reactivity to used but not unused MWF suggests a biocontaminant, probably bacteria or fungi, is the causative antigen in the development of HP in this setting.